Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

BACKGROUND: Excitotoxicity is a central pathological pathway in many neurological diseases with blood–brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin, induces epilepsy and BBB damage in animal models, but the direct effect of kainate on brain endothelial cells has not been studied...

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Podrobná bibliografie
Vydáno v:Fluids Barriers CNS
Hlavní autoři: Barna, Lilla, Walter, Fruzsina R., Harazin, András, Bocsik, Alexandra, Kincses, András, Tubak, Vilmos, Jósvay, Katalin, Zvara, Ágnes, Campos-Bedolla, Patricia, Deli, Mária A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008534/
https://ncbi.nlm.nih.gov/pubmed/32036791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0166-1
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