Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

BACKGROUND: Excitotoxicity is a central pathological pathway in many neurological diseases with blood–brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin, induces epilepsy and BBB damage in animal models, but the direct effect of kainate on brain endothelial cells has not been studied...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Barna, Lilla, Walter, Fruzsina R., Harazin, András, Bocsik, Alexandra, Kincses, András, Tubak, Vilmos, Jósvay, Katalin, Zvara, Ágnes, Campos-Bedolla, Patricia, Deli, Mária A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008534/
https://ncbi.nlm.nih.gov/pubmed/32036791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0166-1
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