Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

BACKGROUND: Excitotoxicity is a central pathological pathway in many neurological diseases with blood–brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin, induces epilepsy and BBB damage in animal models, but the direct effect of kainate on brain endothelial cells has not been studied...

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發表在:Fluids Barriers CNS
Main Authors: Barna, Lilla, Walter, Fruzsina R., Harazin, András, Bocsik, Alexandra, Kincses, András, Tubak, Vilmos, Jósvay, Katalin, Zvara, Ágnes, Campos-Bedolla, Patricia, Deli, Mária A.
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008534/
https://ncbi.nlm.nih.gov/pubmed/32036791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0166-1
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