Protection of cultured brain endothelial cells from cytokine-induced damage by α-melanocyte stimulating hormone

The blood–brain barrier (BBB), an interface between the systemic circulation and the nervous system, can be a target of cytokines in inflammatory conditions. Pro-inflammatory cytokines tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) induce damage in brain endothelial cells and BBB dysfunc...

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Detalhes bibliográficos
Main Authors: András Harazin, Alexandra Bocsik, Lilla Barna, András Kincses, Judit Váradi, Ferenc Fenyvesi, Vilmos Tubak, Maria A. Deli, Miklós Vecsernyés
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018-05-01
Colecção:PeerJ
Assuntos:
Brain endothelial cells
Permeability
α-Melanocyte-stimulating hormone
Cytokines
Tight junction
Blood–brain barrier
Acesso em linha:https://peerj.com/articles/4774.pdf
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