Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds

[Image: see text] A series of compounds (including CCG-1423 and CCG-203971) discovered through an MRTF/SRF-dependent luciferase screen has shown remarkable efficacy in a variety of in vitro and in vivo models, including significant reduction of melanoma metastasis and bleomycin-induced fibrosis. Alt...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Pharmacol Transl Sci
Hlavní autoři: Lisabeth, Erika M., Kahl, Dylan, Gopallawa, Indiwari, Haynes, Sarah E., Misek, Sean A., Campbell, Phillip L., Dexheimer, Thomas S., Khanna, Dinesh, Fox, David A., Jin, Xiangshu, Martin, Brent R., Larsen, Scott D., Neubig, Richard R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006939/
https://ncbi.nlm.nih.gov/pubmed/32039344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00048
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky