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RPEL Proteins Are the Molecular Targets for CCG-1423, an Inhibitor of Rho Signaling
Epithelial–msenchymal transition (EMT) is closely associated with cancer and tissue fibrosis. The nuclear accumulation of myocardin-related transcription factor A (MRTF-A/MAL/MKL1) plays a vital role in EMT. In various cells treated with CCG-1423, a novel inhibitor of Rho signaling, the nuclear accu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928398/ https://ncbi.nlm.nih.gov/pubmed/24558465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089016 |
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