RPEL Proteins Are the Molecular Targets for CCG-1423, an Inhibitor of Rho Signaling

Epithelial–msenchymal transition (EMT) is closely associated with cancer and tissue fibrosis. The nuclear accumulation of myocardin-related transcription factor A (MRTF-A/MAL/MKL1) plays a vital role in EMT. In various cells treated with CCG-1423, a novel inhibitor of Rho signaling, the nuclear accu...

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Hlavní autoři: Hayashi, Ken’ichiro, Watanabe, Bunta, Nakagawa, Yoshiaki, Minami, Saki, Morita, Tsuyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928398/
https://ncbi.nlm.nih.gov/pubmed/24558465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089016
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