Purifying selection of long dsRNA is the first line of defense against false activation of innate immunity

BACKGROUND: Mobile elements comprise a large fraction of metazoan genomes. Accumulation of mobile elements is bound to produce multiple putative double-stranded RNA (dsRNA) structures within the transcriptome. These endogenous dsRNA structures resemble viral RNA and may trigger false activation of t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Barak, Michal, Porath, Hagit T., Finkelstein, Gilad, Knisbacher, Binyamin A., Buchumenski, Ilana, Roth, Shalom Hillel, Levanon, Erez Y., Eisenberg, Eli
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006430/
https://ncbi.nlm.nih.gov/pubmed/32028986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-1937-3
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