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Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance

BACKGROUND: Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans. Technical requirements have limited systematic mapping of editing sites to a small numb...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Porath, Hagit T., Knisbacher, Binyamin A., Eisenberg, Eli, Levanon, Erez Y.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625713/
https://ncbi.nlm.nih.gov/pubmed/28969707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1315-y
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