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DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes

Long terminal repeat retrotransposons (LTR) are widespread in vertebrates and their dynamism facilitates genome evolution. However, these endogenous retroviruses (ERVs) must be restricted to maintain genomic stability. The APOBECs, a protein family that can edit C-to-U in DNA, do so by interfering w...

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Detalles Bibliográficos
Publicado en:Mol Biol Evol
Main Authors: Knisbacher, Binyamin A., Levanon, Erez Y.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866542/
https://ncbi.nlm.nih.gov/pubmed/26541172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv239
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