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Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets
A-to-I RNA editing is an important post-transcriptional modification, known to be altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA biogenesis and function, as well as many miRNA recognition sites. However, the full extent of the effect of editing on regulation...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758889/ https://ncbi.nlm.nih.gov/pubmed/29165639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1176 |
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