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Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis. MANF has a cytoprotective function, shown in the central nervous system neurons and pancreatic beta cells. Here, we repo...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005028/ https://ncbi.nlm.nih.gov/pubmed/32029702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2286-6 |
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