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Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain
The tumor suppressor gene p53 encodes a transcriptional activator that has two transactivation domains (TAD) located in its amino terminus. These two TAD can transactivate genes independently, and at least one TAD is required for p53 transactivation function. The 1st TAD (a.a. 1‐40) is essential for...
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| Publié dans: | Cancer Sci |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7004532/ https://ncbi.nlm.nih.gov/pubmed/31834974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14279 |
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