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FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development
FMS‐like tyrosine kinase 3 (FLT3) is a type III receptor tyrosine kinase that plays an important role in hematopoietic cell survival, proliferation and differentiation. The most clinically important point is that mutation of the FLT3 gene is the most frequent genetic alteration and a poor prognostic...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7004512/ https://ncbi.nlm.nih.gov/pubmed/31821677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14274 |
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