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The evolving role of FLT3 inhibitors in acute myeloid leukemia: quizartinib and beyond

Acute myeloid leukemia remains associated with poor outcomes despite advances in our understanding of the complicated molecular events driving leukemogenesis and malignant progression. Those patients harboring mutations in the FLT3 receptor tyrosine kinase have a particularly poor prognosis; however...

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Détails bibliographiques
Auteurs principaux: Wander, Seth A., Levis, Mark J., Fathi, Amir T.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031904/
https://ncbi.nlm.nih.gov/pubmed/24883179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620714532123
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