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Incorporating FLT3 inhibitors into acute myeloid leukemia treatment regimens
FMS-Like-Tyrosine kinase-3 (FLT3) mutations are found in about 30% of cases of acute myeloid leukemia and confer an increased relapse rate and reduced overall survival. Targeting of this tyrosine kinase by direction inhibition is the focus of both preclinical and clinical research in AML. Several mo...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031857/ https://ncbi.nlm.nih.gov/pubmed/18452067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190801895352 |
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