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Bench to Bedside Targeting of FLT3 in Acute Leukemia

FMS-Like-Tyrosine kinase-3 (FLT3) mutations are found in about 30% of cases of acute myeloid leukemia and confer an increased relapse rate and reduced overall survival. Targeting this tyrosine kinase by direction inhibition is the focus of both preclinical and clinical research in AML. Several molec...

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Detaylı Bibliyografya
Asıl Yazarlar: Pratz, Keith W., Levis, Mark J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023996/
https://ncbi.nlm.nih.gov/pubmed/20370649
Etiketler: Etiketle
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