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Emerging treatment paradigms with FLT3 inhibitors in acute myeloid leukemia
Mutations in the fms-like tyrosine kinase 3 (FLT3) gene are detected in approximately one-third of patients with newly diagnosed acute myeloid leukemia (AML). These consist of the more common FLT3-internal tandem duplication (ITD) in approximately 20–25% of AML cases, and point mutations in the tyro...
Enregistré dans:
| Publié dans: | Ther Adv Hematol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
SAGE Publications
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378516/ https://ncbi.nlm.nih.gov/pubmed/30800259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620719827310 |
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