TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects

Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll-like receptor 4 (TLR4) activation by bacterial lipopolysaccharide (LPS) is the key mediator of cytokine storm and septic shock that can cause severe tissue damage limiting a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haderski, Gary J., Kandar, Bojidar M., Brackett, Craig M., Toshkov, Ilia M., Johnson, Christopher P., Paszkiewicz, Geraldine M., Natarajan, Venkatesh, Gleiberman, Anatoli S., Gudkov, Andrei V., Burdelya, Lyudmila G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004342/
https://ncbi.nlm.nih.gov/pubmed/32027657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227940
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados