Lanean...
Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213
The role of Phe213 in the allosteric mechanism of human cytochrome P450 CYP3A4 was studied using a combination of progesterone (PGS) and carbamazepine (CBZ) as probe substrates. We expressed, purified and incorporated in POPC Nanodiscs three mutants, F213A, F213S, and F213Y, and compared them with t...
Gorde:
| Argitaratua izan da: | Biochemistry |
|---|---|
| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7003538/ https://ncbi.nlm.nih.gov/pubmed/30785734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01268 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|