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Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain
Prions are pathological isoforms of the cellular prion protein that is responsible for transmissible spongiform encephalopathies (TSE). Cellular prion protein interacts with copper, Cu(II), through octarepeat and nonoctarepeat (non-OR) binding sites. The molecular details of Cu(II) coordination with...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002980/ https://ncbi.nlm.nih.gov/pubmed/31952810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.025 |
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