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Structural Consequences of Copper Binding to the Prion Protein

Prion, or PrP(Sc), is the pathological isoform of the cellular prion protein (PrP(C)) and it is the etiological agent of transmissible spongiform encephalopathies (TSE) affecting humans and animal species. The most relevant function of PrP(C) is its ability to bind copper ions through its flexible N...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Salzano, Giulia, Giachin, Gabriele, Legname, Giuseppe
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721516/
https://ncbi.nlm.nih.gov/pubmed/31349611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080770
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