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Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease

[Image: see text] Chronic wasting disease (CWD) is a highly infectious prion disease of cervids. Accumulation of prions, the disease-specific structural conformers of the cellular prion protein (PrP(C)), in the central nervous system, is the key pathological event of the disorder. The analysis of ce...

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Publicat a:ACS Omega
Autors principals: Slapšak, Urška, Salzano, Giulia, Ilc, Gregor, Giachin, Gabriele, Bian, Jifeng, Telling, Glenn, Legname, Giuseppe, Plavec, Janez
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882122/
https://ncbi.nlm.nih.gov/pubmed/31788624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02824
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