טוען...

Quinacrine promotes replication and conformational mutation of chronic wasting disease prions

Quinacrine’s ability to reduce levels of pathogenic prion protein (PrP(Sc)) in mouse cells infected with experimentally adapted prions led to several unsuccessful clinical studies in patients with prion diseases, a 10-y investment to understand its mechanism of action, and the production of related...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Bian, Jifeng, Kang, Hae-Eun, Telling, Glenn C.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000840/
https://ncbi.nlm.nih.gov/pubmed/24711410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322377111
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!