Characterization of Conformation-dependent Prion Protein Epitopes

Whereas prion replication involves structural rearrangement of cellular prion protein (PrP(C)), the existence of conformational epitopes remains speculative and controversial, and PrP transformation is monitored by immunoblot detection of PrP(27–30), a protease-resistant counterpart of the pathogeni...

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Detalhes bibliográficos
Main Authors: Kang, Hae-Eun, Weng, Chu Chun, Saijo, Eri, Saylor, Vicki, Bian, Jifeng, Kim, Sehun, Ramos, Laylaa, Angers, Rachel, Langenfeld, Katie, Khaychuk, Vadim, Calvi, Carla, Bartz, Jason, Hunter, Nora, Telling, Glenn C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481321/
https://ncbi.nlm.nih.gov/pubmed/22948149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395921
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