Characterization of Conformation-dependent Prion Protein Epitopes

Whereas prion replication involves structural rearrangement of cellular prion protein (PrP(C)), the existence of conformational epitopes remains speculative and controversial, and PrP transformation is monitored by immunoblot detection of PrP(27–30), a protease-resistant counterpart of the pathogeni...

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Detalles Bibliográficos
Autores principales: Kang, Hae-Eun, Weng, Chu Chun, Saijo, Eri, Saylor, Vicki, Bian, Jifeng, Kim, Sehun, Ramos, Laylaa, Angers, Rachel, Langenfeld, Katie, Khaychuk, Vadim, Calvi, Carla, Bartz, Jason, Hunter, Nora, Telling, Glenn C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481321/
https://ncbi.nlm.nih.gov/pubmed/22948149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395921
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