Cell-Based Quantification of Chronic Wasting Disease Prions

Cell-based measurement of prion infectivity is currently restricted to experimental strains of mouse-adapted scrapie. Having isolated cell cultures with susceptibility to prions from diseased elk, we describe a modification of the scrapie cell assay allowing evaluation of prions causing chronic wast...

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Bibliographic Details
Main Authors: Bian, Jifeng, Napier, Dana, Khaychuck, Vadim, Angers, Rachel, Graham, Catherine, Telling, Glenn
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916541/
https://ncbi.nlm.nih.gov/pubmed/20519392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00633-10
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