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mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion
How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002553/ https://ncbi.nlm.nih.gov/pubmed/32024827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14032-1 |
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