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LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
The Hippo and mTORC1 pathways are the two predominant growth-control pathways that dictate proper organ development. We therefore explored a possible crosstalk between these two functional relevant pathways to coordinate their growth-control functions. We found that the LATS1/2 kinases, the core com...
שמור ב:
| הוצא לאור ב: | Nat Cell Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7076906/ https://ncbi.nlm.nih.gov/pubmed/32015438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0463-6 |
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