LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

The Hippo and mTORC1 pathways are the two predominant growth-control pathways that dictate proper organ development. We therefore explored a possible crosstalk between these two functional relevant pathways to coordinate their growth-control functions. We found that the LATS1/2 kinases, the core com...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Cell Biol
मुख्य लेखकों: Gan, Wenjian, Dai, Xiaoming, Dai, Xiangpeng, Xie, Jun, Yin, Shasha, Zhu, Junjie, Wang, Chen, Liu, Yuchen, Guo, Jianping, Wang, Min, Liu, Jing, Hu, Jia, Quinton, Ryan J., Ganem, Neil J., Liu, Pengda, Asara, John M., Pandolfi, Pier Paolo, Yang, Yingzi, He, Zhigang, Gao, Guangping, Wei, Wenyi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076906/
https://ncbi.nlm.nih.gov/pubmed/32015438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0463-6
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन