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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
The mechanistic target of rapamycin (mTOR) has a key role in the integration of various physiological stimuli to regulate several cell growth and metabolic pathways(1). mTOR primarily functions as a catalytic subunit in two structurally related but functionally distinct multi-component kinase comple...
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| Vydáno v: | Nature |
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| Hlavní autoři: | , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695540/ https://ncbi.nlm.nih.gov/pubmed/28489822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22344 |
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