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mTORC1 and mTORC2 coordinate early NK cell development by differentially inducing E4BP4 and T-bet

Natural killer (NK) cell development is a multistep process that requires a variety of signals and transcription factors. The lack of mammalian target of rapamycin (mTOR) kinase severely impairs NK cell development in mice. mTOR binds to Raptor and Rictor to form two complexes, mTORC1 and mTORC2, re...

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Foilsithe in:Cell Death Differ
Main Authors: Li, Dan, Wang, Yuande, Yang, Meixiang, Dong, Zhongjun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184794/
https://ncbi.nlm.nih.gov/pubmed/33462410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00715-6
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