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mTORC1 and mTORC2 coordinate early NK cell development by differentially inducing E4BP4 and T-bet
Natural killer (NK) cell development is a multistep process that requires a variety of signals and transcription factors. The lack of mammalian target of rapamycin (mTOR) kinase severely impairs NK cell development in mice. mTOR binds to Raptor and Rictor to form two complexes, mTORC1 and mTORC2, re...
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| Pubblicato in: | Cell Death Differ |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184794/ https://ncbi.nlm.nih.gov/pubmed/33462410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00715-6 |
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