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The Plasminogen Activator Inhibitor-1 Paradox in Cancer: A Mechanistic Understanding

The paradoxical pro-tumorigenic function of plasminogen activator inhibitor 1 (PAI-1, aka Serpin E1) in cancer progression and metastasis has been the subject of an abundant scientific literature that has pointed to a pro-angiogenic role, a growth and migration stimulatory function and an anti-apopt...

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Kubala, Marta Helena, DeClerck, Yves Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001780/
https://ncbi.nlm.nih.gov/pubmed/31734763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09806-4
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