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Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment

siRNA and shRNA-mediated knock down (KD) methods of regulating gene expression are invaluable tools for understanding gene and protein function. However, in the case that the KD of the protein of interest has a lethal effect on cells or the anticipated effect of the KD is time-dependent, uncondition...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Kubala, Marta H., DeClerck, Yves A.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755478/
https://ncbi.nlm.nih.gov/pubmed/29286360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56333
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