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Plasminogen activator inhibitor-1 promotes the recruitment and polarization of macrophages in cancer
Plasminogen activator inhibitor-1 (PAI-1) has a pro-tumorigenic function via its pro-angiogenic and anti-apoptotic activities. Here we demonstrate that PAI-1 promoted the recruitment and M2 polarization of monocytes/macrophages through different structural domains. Its LRP1 interacting domain regula...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6876299/ https://ncbi.nlm.nih.gov/pubmed/30463014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.082 |
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