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Protumorigenic Activity of Plasminogen Activator Inhibitor-1 Through an Antiapoptotic Function
BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is a protease inhibitor but is paradoxically associated with poor outcomes in cancer patients. However, the mechanisms of its effects on tumor cells have not been explored. METHODS: Endogenous PAI-1 in human tumor cell lines (HT-1080, A549, HCT-1...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529616/ https://ncbi.nlm.nih.gov/pubmed/22984202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs377 |
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