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Synthesis of Myrocin G, the Putative Active Form of the Myrocin Antitumor Antibiotics
The antiproliferative antimicrobial fungal metabolites known as the myrocins have been proposed to cross-link DNA by double nucleotide addition. However, the nature of the DNA-reactive species is ambiguous, as myrocins have been isolated as functionally distinct 5-hydroxy-γ-lactone and diosphenol is...
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| Udgivet i: | J Am Chem Soc |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7001008/ https://ncbi.nlm.nih.gov/pubmed/30415540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10891 |
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