Anticellular and Antitumor Activity of Duocarmycins, Novel Antitumor Antibiotics

The anticellular and antitumor activities of novel antitumor antibiotics, duocarmycins (DUMs), were examined against human and murine tumor cells. DUMs consist of live compounds, A, B(1), B(2), C(1), and C(2), which possess a pharmacophore similar to that of CC‐1065, a previously isolated antibiotic...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Gomi, Katsushige, Kobayashi, Eiji, Miyoshi, Katsunori, Ashizawa, Tadashi, Okamoto, Akihiko, Ogawa, Tatsuhiro, Katsumata, Shigeo, Mihara, Akira, Okabe, Masami, Hirata, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1992
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918644/
https://ncbi.nlm.nih.gov/pubmed/1544867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02360.x
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