Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents

Current treatment for combatting Chagas disease, a life-threatening illness caused by the kinetoplastid protozoan parasite Trypanosoma cruzi is inadequate, and thus the discovery of new antiparasitic compounds is of prime importance. Previous studies identified the indirubins, a class of ATP kinase...

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Vydáno v:Virulence
Hlavní autoři: Efstathiou, Antonia, Meira, Cássio Santana, Gaboriaud-Kolar, Nicolas, Bastos, Tanira Matutino, Rocha, Vinícius Pinto Costa, Vougogiannopoulou, Konstantina, Skaltsounis, Alexios-Leandros, Smirlis, Despina, Soares, Milena Botelho Pereira
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000199/
https://ncbi.nlm.nih.gov/pubmed/30387370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2018.1532242
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