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Tracing the Origin and Evolution of Pseudokinases Across the Tree of Life
Protein phosphorylation by eukaryotic protein kinases (ePKs) represents a fundamental mechanism of cell signaling in all organisms. In model vertebrates, ~10% of ePKs are classified as pseudokinases, which possess amino acid changes within the catalytic machinery of the kinase domain that distinguis...
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| Publicado en: | Sci Signal |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6997932/ https://ncbi.nlm.nih.gov/pubmed/31015289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aav3810 |
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