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Rethinking Pseudokinases
Pseudokinases lack conservation of one or more of the catalytic residues in the kinase core and as a consequence are typically thought to be catalytically inactive. New work by Mukherjee et al. (2008) challenges this assumption. They show that the pseudokinase domain of CASK (Ca(2+)/calmodulin activ...
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| Publicado en: | Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226312/ https://ncbi.nlm.nih.gov/pubmed/18423189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.005 |
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