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Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease

The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved unique features distinguishing them from all other protein kinases. The atypical pseudokinase domain retains a regulated binding platform for substrates, which are ubiquitinated by context-specific E3 l...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Eyers, Patrick A., Keeshan, Karen, Kannan, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382568/
https://ncbi.nlm.nih.gov/pubmed/27908682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.11.002
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