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Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease

The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved unique features distinguishing them from all other protein kinases. The atypical pseudokinase domain retains a regulated binding platform for substrates, which are ubiquitinated by context-specific E3 l...

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Vydáno v:Trends Cell Biol
Hlavní autoři: Eyers, Patrick A., Keeshan, Karen, Kannan, Natarajan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science Publishers 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382568/
https://ncbi.nlm.nih.gov/pubmed/27908682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.11.002
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