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Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease
The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved unique features distinguishing them from all other protein kinases. The atypical pseudokinase domain retains a regulated binding platform for substrates, which are ubiquitinated by context-specific E3 l...
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Publicado no: | Trends Cell Biol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Science Publishers
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382568/ https://ncbi.nlm.nih.gov/pubmed/27908682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2016.11.002 |
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