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Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation

Site-selective bioconjugation to native protein residues is a powerful tool for protein functionalization, with cysteine and lysine side chains being the most common points for attachment owing to their high nucleophilicity. We now report a strategy for histidine modification using thiophosphorodich...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Jia, Shang, He, Dan, Chang, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996876/
https://ncbi.nlm.nih.gov/pubmed/31017395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11912
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