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Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation
Site-selective bioconjugation to native protein residues is a powerful tool for protein functionalization, with cysteine and lysine side chains being the most common points for attachment owing to their high nucleophilicity. We now report a strategy for histidine modification using thiophosphorodich...
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| Publicat a: | J Am Chem Soc |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996876/ https://ncbi.nlm.nih.gov/pubmed/31017395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11912 |
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