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Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation
Site-selective bioconjugation to native protein residues is a powerful tool for protein functionalization, with cysteine and lysine side chains being the most common points for attachment owing to their high nucleophilicity. We now report a strategy for histidine modification using thiophosphorodich...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996876/ https://ncbi.nlm.nih.gov/pubmed/31017395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11912 |
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