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A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation
We report a data-driven, physical organic approach to the development of new methionine-selective bioconjugation reagents with tunable adduct stabilities. Statistical modeling of structural features described by intrinsic physical organic parameters was applied to the development of a predictive mod...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781863/ https://ncbi.nlm.nih.gov/pubmed/31361488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b04744 |
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