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PTEN Mouse Models of Cancer Initiation and Progression

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is one of the most frequently mutated, deleted, and functionally inactivated tumor suppressor genes in human cancer. PTEN is found mutated both somatically and in the germline of patients with PTEN hamartoma tumor syndrome (PHTS). PTEN e...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Med
Main Authors: Lee, Yu-Ru, Pandolfi, Pier Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996448/
https://ncbi.nlm.nih.gov/pubmed/31570383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a037283
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