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PTEN Mouse Models of Cancer Initiation and Progression

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is one of the most frequently mutated, deleted, and functionally inactivated tumor suppressor genes in human cancer. PTEN is found mutated both somatically and in the germline of patients with PTEN hamartoma tumor syndrome (PHTS). PTEN e...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Lee, Yu-Ru, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996448/
https://ncbi.nlm.nih.gov/pubmed/31570383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a037283
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