Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron degenerative disease. TDP-43 (TAR DNA-binding protein 43) and FUS (fused in sarcoma) are aggregation-prone RNA-binding proteins that in ALS can mislocalize to the cytoplasm of affected motor neuron cells, often forming cytoplasmic aggregate...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Liu, Guangbo, Byrd, Aaron, Warner, Amanda N., Pei, Fen, Basha, Eman, Buchanan, Allison, Buchan, J. Ross
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996276/
https://ncbi.nlm.nih.gov/pubmed/31767634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00256-19
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller